Perform
A patient or caregiver records a guided movement task with a phone or completes a standardized drawing task on a tablet.
Highlighted research · At-home digital biomarkers
Measuring rare disease between clinic visits.
Rare neurologic disease unfolds between infrequent visits. We're testing whether motor tasks captured with everyday devices can provide a more continuous picture of functional state.
Read the rationale
Rationale
A clinic visit is one frame.
Rare-disease cohorts are small, geographically dispersed, and commonly evaluated through brief, infrequent examinations. Clinical scores remain essential, but they can compress subtle variation and make progression or treatment response difficult to see. The measurement should be able to follow the patient home.
Hypothesis
Repeated smartphone video and tablet-based motor tasks can transform movement and coordination into interpretable, patient-specific trajectories of disease state.
Smartphone videoBody poseTablet spiralClinical anchor
What we’re building
From digitized tasks to a longitudinal phenotype.
Short assessments designed to fit into home life while staying tied to established clinical measures.
Quantify
Pose trajectories, stability, symmetry, speed, accuracy, timing, and steadiness become digital biomarkers.
Follow
Repeated measurements form an individualized trajectory anchored to clinical assessments, treatment, and time.
The exam itself doesn't change. We capture its tasks digitally, quantify them, and repeat them at home, so progression and treatment response become visible between visits.